Acute Myeloid Leukemia Research Today is a free monthly online journal that collates and summarizes the latest research about Acute Myeloid Leukemia, including details on aml, symptoms, treatment, information.

Volume 2 (2005), Issue 2 (February)

1. GATA1, cytidine deaminase, and the high cure rate of Down syndrome children with acute megakaryocytic leukemia.
   J Natl Cancer Inst, 97(3): 226-31. [Abstract] [Full-text]
2. CA 125 levels in patients with non-Hodgkin lymphoma and other hematologic malignancies.
   Clin Lab Haematol, 27(1): 51-5. [Abstract] [Full-text]
3. HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo.
   Blood, 105(4): 1456-66. [Abstract] [Full-text]
4. Combination of the histone deacetylase inhibitor LBH589 and the hsp90 inhibitor 17-AAG is highly active against human CML-BC cells and AML cells with activating mutation of FLT-3.
   Blood, 105(4): 1768-76. [Abstract] [Full-text]
5. Selective cytotoxicity and telomere damage in leukemia cells using the telomerase inhibitor BIBR1532.
   Blood, 105(4): 1742-9. [Abstract] [Full-text]
6. Pim-1 is up-regulated by constitutively activated FLT3 and plays a role in FLT3-mediated cell survival.
   Blood, 105(4): 1759-67. [Abstract] [Full-text]
7. Farnesyltransferase inhibitors interact synergistically with the Chk1 inhibitor UCN-01 to induce apoptosis in human leukemia cells through interruption of both Akt and MEK/ERK pathways and activation of SEK1/JNK.
   Blood, 105(4): 1706-16. [Abstract] [Full-text]
8. Differentiation of acute and chronic myeloid leukemic blasts into the dendritic cell lineage: analysis of various differentiation-inducing signals.
   Cancer Immunol Immunother, 54(1): 25-36. [Abstract] [Full-text]
9. Acquired hemoglobin H disease in a patient with aplastic anemia evolving into acute myeloid leukemia.
   Sao Paulo Med J, 122(6): 273-5. [Abstract] [Full-text]
10. Myositis complicating viridans streptococcal sepsis in childhood leukemia.
    Pediatr Blood Cancer, 44(3): 277-9. [Abstract] [Full-text]
11. A wide role for NOTCH1 signaling in acute leukemia.
    Cancer Lett, 219(1): 113-20. [Abstract] [Full-text]
12. Secondary leukemia after first-line high-dose chemotherapy for patients with advanced germ cell cancer.
    J Cancer Res Clin Oncol, 131(4): 255-60. [Abstract] [Full-text]
13. Fludarabine-based conditioning for allogeneic stem cell transplantation for multiply transfused patients with Fanconi's anemia.
    Bone Marrow Transplant, 35(4): 341-3. [Abstract] [Full-text]
14. Acute myeloid leukemia with deletion 9q within a noncomplex karyotype is associated with CEBPA loss-of-function mutations.
    Genes Chromosomes Cancer, 42(4): 427-32. [Abstract] [Full-text]
15. A cross-linker-sensitive myeloid leukemia cell line from a 2-year-old boy with severe Fanconi anemia and biallelic FANCD1/BRCA2 mutations.
    Genes Chromosomes Cancer, 42(4): 404-15. [Abstract] [Full-text]
16. Centromeric breakage and highly rearranged chromosome derivatives associated with mutations of TP53 are common in therapy-related MDS and AML after therapy with alkylating agents: an M-FISH study.
    Genes Chromosomes Cancer, 42(4): 358-71. [Abstract] [Full-text]
17. Prescription drug use and risk of acute myeloid leukemia by French-American-British subtype: results from a Los Angeles County case-control study.
    Int J Cancer, 114(4): 634-8. [Abstract] [Full-text]
18. Arsenic trioxide represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60.
    J Cell Biochem, 94(4): 695-707. [Abstract] [Full-text]
19. RGS2 is an important target gene of Flt3-ITD mutations in AML and functions in myeloid differentiation and leukemic transformation.
    Blood, 105(5): 2107-14. [Abstract] [Full-text]
20. Therapy-related acute myeloid leukemia-like MLL rearrangements are induced by etoposide in primary human CD34+ cells and remain stable after clonal expansion.
    Blood, 105(5): 2124-31. [Abstract] [Full-text]
21. Analysis of concerted expression of angiogenic growth factors in acute myeloid leukemia: expression of angiopoietin-2 represents an independent prognostic factor for overall survival.
    J Clin Oncol, 23(6): 1109-17. [Abstract] [Full-text]
22. Cryptic 5' MLL gene insertion in an X-chromosome in acute myeloblastic leukemia.
    Cancer Genet Cytogenet, 157(2): 178-80. [Abstract] [Full-text]
23. Rearrangement of the MLL gene in acute myeloblastic leukemia: report of two rare translocations.
    Cancer Genet Cytogenet, 157(2): 169-74. [Abstract] [Full-text]
24. NUP98 is fused to HOXA9 in a variant complex t(7;11;13;17) in a patient with AML-M2.
    Cancer Genet Cytogenet, 157(2): 151-6. [Abstract] [Full-text]
25. Cytoprotection in acute myelogenous leukemia (AML) therapy.
    Semin Oncol, 31(6): 67-73. [Abstract] [Full-text]
26. t(9;11)(p22;p15) with NUP98-LEDGF fusion gene in pediatric acute myeloid leukemia.
    Leuk Res, 29(4): 467-70. [Abstract] [Full-text]
27. Acquired PTPN11 mutations occur rarely in adult patients with myelodysplastic syndromes and chronic myelomonocytic leukemia.
    Leuk Res, 29(4): 459-62. [Abstract] [Full-text]
28. Imatinib mesylate in the treatment of Core Binding Factor leukemias with KIT mutations. A report of three cases.
    Leuk Res, 29(4): 397-400. [Abstract] [Full-text]
29. Prognostic value of real-time quantitative PCR (RQ-PCR) in AML with t(8;21).
    Leukemia, 19(3): 367-72. [Abstract] [Full-text]
30. CEBPA point mutations in hematological malignancies.
    Leukemia, 19(3): 329-34. [Abstract] [Full-text]
31. Reliable quantification of hematopoietic chimerism after allogeneic transplantation for acute leukemia using amplification by real-time PCR of null alleles and insertion/deletion polymorphisms.
    Leukemia, 19(3): 336-43. [Abstract] [Full-text]
32. Gene expression profile reveals deregulation of genes with relevant functions in the different subclasses of acute myeloid leukemia.
    Leukemia, 19(3): 402-9. [Abstract] [Full-text]
33. Value of chemotherapy before allogeneic hematopoietic stem cell transplantation from an HLA-identical sibling donor for myelodysplastic syndrome.
    Leukemia, 19(3): 396-401. [Abstract] [Full-text]
34. Distinct gene expression patterns associated with FLT3- and NRAS-activating mutations in acute myeloid leukemia with normal karyotype.
    Oncogene, 24(9): 1580-8. [Abstract] [Full-text]
35. CEBPalpha mutations in childhood acute myeloid leukemia.
    Leukemia, 19(3): 410-4. [Abstract] [Full-text]
36. 5-Aza-2'-deoxycytidine induces p21WAF expression by demethylation of p73 leading to p53-independent apoptosis in myeloid leukemia.
    Int J Cancer, 114(5): 683-95. [Abstract] [Full-text]
37. Massive myeloid sarcoma affecting the central nervous system, mediastinum, retroperitoneum, liver, and rectum associated with acute myeloblastic leukaemia: a case report.
    J Clin Pathol, 58(3): 325-7. [Abstract] [Full-text]
38. Inhibitory anti-FLT3 antibodies are capable of mediating antibody-dependent cell-mediated cytotoxicity and reducing engraftment of acute myelogenous leukemia blasts in nonobese diabetic/severe combined immunodeficient mice.
    Cancer Res, 65(4): 1514-22. [Abstract] [Full-text]
39. Interplay of RUNX1/MTG8 and DNA methyltransferase 1 in acute myeloid leukemia.
    Cancer Res, 65(4): 1277-84. [Abstract] [Full-text]
40. CD34 expression in native human acute myelogenous leukemia blasts: differences in CD34 membrane molecule expression are associated with different gene expression profiles.
    Cytometry B Clin Cytom, 64(1): 18-27. [Abstract] [Full-text]

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