Acute Myeloid Leukemia Research Today is a free monthly online journal that collates and summarizes the latest research about Acute Myeloid Leukemia, including details on aml, symptoms, treatment, information.

Volume 4 (2007), Issue 4 (April)

1. Activated intrinsic apoptosis pathway is a key related prognostic parameter in acute myeloid leukemia.
   J Clin Oncol, 25(10): 1209-15. [Abstract] [Full-text]
2. Fluorescent in situ hybridization (FISH) in bone marrow and peripheral blood of leukemia patients: implications for occupational surveillance.
   Mutat Res, 629(1): 24-31. [Abstract] [Full-text]
3. Establishment of a novel childhood acute myeloid leukaemia cell line, KOPM-88, containing partial tandem duplication of the MLL gene and an in vivo model for childhood acute myeloid leukaemia using NOD/SCID mice.
   Br J Haematol, 137(3): 221-32. [Abstract] [Full-text]
4. ABT-869, a multitargeted receptor tyrosine kinase inhibitor: inhibition of FLT3 phosphorylation and signaling in acute myeloid leukemia.
   Blood, 109(8): 3400-8. [Abstract] [Full-text]
5. Oridonin, a diterpenoid extracted from medicinal herbs, targets AML1-ETO fusion protein and shows potent antitumor activity with low adverse effects on t(8;21) leukemia in vitro and in vivo.
   Blood, 109(8): 3441-50. [Abstract] [Full-text]
6. Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.
   Blood, 109(8): 3509-12. [Abstract] [Full-text]
7. Chemotherapy exposure increases leukemia cell stiffness.
   Blood, 109(8): 3505-8. [Abstract] [Full-text]
8. Analysis of histone modification around the CpG island region of the p15 gene in acute myeloblastic leukemia.
   Leuk Res, 31(5): 611-21. [Abstract] [Full-text]
9. Granzyme B induction signalling pathway in acute myeloid leukemia cell lines stimulated by tumor necrosis factor alpha and Fas ligand.
   Cell Signal, 19(6): 1132-40. [Abstract] [Full-text]
10. Equivalent survival for sibling and unrelated donor allogeneic stem cell transplantation for acute myelogenous leukemia.
    Biol Blood Marrow Transplant, 13(5): 601-7. [Abstract] [Full-text]
11. Concurrent transcriptional deregulation of AML1/RUNX1 and GATA factors by the AML1-TRPS1 chimeric gene in t(8;21)(q24;q22) acute myeloid leukemia.
    Blood, 109(9): 4023-7. [Abstract] [Full-text]
12. The C/EBPdelta tumor suppressor is silenced by hypermethylation in acute myeloid leukemia.
    Blood, 109(9): 3895-905. [Abstract] [Full-text]
13. Results of a HOVON/SAKK donor versus no-donor analysis of myeloablative HLA-identical sibling stem cell transplantation in first remission acute myeloid leukemia in young and middle-aged adults: benefits for whom?
    Blood, 109(9): 3658-66. [Abstract] [Full-text]
14. Flt3 is dispensable to the Hoxa9/Meis1 leukemogenic cooperation.
    Blood, 109(9): 4020-2. [Abstract] [Full-text]
15. Polymorphisms in DNA repair genes and therapeutic outcomes of AML patients from SWOG clinical trials.
    Blood, 109(9): 3936-44. [Abstract] [Full-text]
16. A leukemia fusion protein attenuates the spindle checkpoint and promotes aneuploidy.
    Blood, 109(9): 3963-71. [Abstract] [Full-text]
17. Clinical implications of minimal residual disease monitoring by quantitative polymerase chain reaction in acute myeloid leukemia patients bearing nucleophosmin (NPM1) mutations.
    Leukemia, 21(5): 998-1004. [Abstract] [Full-text]
18. The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion.
    Leukemia, 21(5): 886-96. [Abstract] [Full-text]
19. MicroRNA miR-181a correlates with morphological sub-class of acute myeloid leukaemia and the expression of its target genes in global genome-wide analysis.
    Leukemia, 21(5): 912-6. [Abstract] [Full-text]
20. Discovery of epigenetically silenced genes in acute myeloid leukemias.
    Leukemia, 21(5): 1026-34. [Abstract] [Full-text]
21. AS602868, a dual inhibitor of IKK2 and FLT3 to target AML cells.
    Leukemia, 21(5): 877-85. [Abstract] [Full-text]
22. Unbalanced translocation der(1;7)(q10;p10) defines a unique clinicopathological subgroup of myeloid neoplasms.
    Leukemia, 21(5): 992-7. [Abstract] [Full-text]

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